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But additional studies showed that it did not sufficiently reduce cholesterol to warrant its use as a drug. pension reform In 1988, P&G withdrew the application. In 1987, the company filed a food additive petition for the approval of the use of olestra pension reform as a calorie-free replacement for fat in shortening and cooking oil. In 1990, it amended the petition to limit olestra's use to 100 percent replacement for conventional fats in the preparation of savory snacks, such as potato chips, cheese puffs, pension reform and crackers. P&G also is seeking approval for olestra in Canada and the United Kingdom. Olestra Studies Since 1987, P&G has submitted to FDA more than 150 studies on olestra's safety. These include: animal and human studies to determine whether olestra breaks down in the digestive tract animal studies to determine how much, if any, olestra is absorbed into the body animal studies to determine whether olestra can cause birth defects animal studies to determine whether a diet containing olestra is associated with a higher incidence of cancer animal and human studies to determine olestra's effects on absorption of the fat-soluble vitamins and five key water-soluble nutrients that are hard to absorb or are limited in the U.S.
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