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total mortality than those with lower cholesterol levels, effectively turning aging person the low-fat hypothesis on its head. Meanwhile, in the massive Nurses' Health Study involving almost 99,000 nurses aged 30-55 and run by researchers from Harvard since 1976, an analysis in 1997 (Hu et al "Fat intake and the risk of CHD in women," 33: 1491, New England Journal of Medicine, 1997) of CHD risks and dietary fat found some association between 939 cases of developing coronary heart disease among 80,200 of these women reported over 14 years and animal and aging person saturated fat intake, but nothing significant. If there was aging person any effect, it was "consistent with the small-to-negligible effect predicted by metabolic studies." Another way of putting it: No big deal. On total fat and cholesterol intake there was no significant relation to intake and CHD. Indeed, a 1998 review in the Journal of Clinical Epidemiology of the low fat-cholesterol-CHD thesis found that out of a total of 27 studies involving more than 150,000 subjects, in only three cohorts did patients with CHD consume more fat than the controls.
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