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In the much-vaunted Framingham Heart Study — trans fat where 5,200 men and women in Framingham, Mass., have been trans fat extensively studied and reported on in over 1,000 published trans fat studies since 1948 — high cholesterol was not associated with increased heart disease risk after age 47. After age 47, in fact, those whose cholesterol went down had the highest risk of having a heart attack. "For each 1 mg/dl drop of cholesterol there was an 11 percent increase in coronary and total mortality," reported the study's authors. Harvard researcher Walter Willett acknowledged to science writer Gary Taubes in last Sunday's New York Times Magazine cover story, "What If Fat Doesn't Make You Fat," that though our cholesterol levels have been falling, the incidence of heart disease has not. "That is very disconcerting. It suggests that something else bad is happening," Willett commented.
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