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| consumer information, health calculators, policy analysis, fatty liver of pregnancy , food pyramid, eris free, saturated, plump butt , artificial intelligence, blood vessel, geriatric, effects, | The authors caution, however, that further studies are needed to determine whether CD36 is indeed the elusive fat sensor, how it signals fat to the taste fatty vautin bud, and, ultimately, why that prompts craving. "The sensory experience of food can be a primary reinforcer of intake," writes Nada Abumrad of Washington University in an accompanying commentary. "As more is learned about the specificity and mechanism of this receptor's function, it may be possible to devise strategies to treat some forms of obesity." --David Biello RELATED LINKS: fatty vautin Study Shows Fatty Foods Really Do Taste Good Not All fatty vautin Bitters Taste the Same Making Sense of Taste Hunger Intensifies Taste, Study Shows Researchers Discover Taste Receptor for Amino Acids Why Cats Don't Cotton to Sweets Explained EXCLUSIVE ONLINE ISSUES & SPECIAL EDITIONS The Child's Mind A Matter of Time The Nanotech Revolution NEWS FROM OUR PARTNER The Promise of eTherapy A Pacemaker for Depression See your ad here SIGN UP FOR FREE E-MAIL NEWSLETTERS FROM SCIENTIFICAMERICAN.COM |
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| ADVERTISEMENT (article continues below) Researchers have long debated whether a sensor for fat existed, given that many animals display an innate attraction to fats. To determine whether CD36--a protein expressed in the taste buds--might be the culprit, a team at the University policy analysis of Bourgogne devised an experiment using mice that had been genetically modified to lack CD36. These mice, along with a group of wild mice were fed two solutions: one laced with fat and one containing xanthan gum policy analysis to mimic fat's mouthfeel. Wild mice craved the fatty solution. The mice missing CD36, in policy analysis contrast, showed no preference either way. In addition, neither group exhibited a change in either their desire for sugar or aversion to quinine, indicating that CD36's effect was limited to fats. Furthermore, removal of the CD36 gene in rats prevented their digestive tracts from preparing the various gastric juices necessary to digest fat. "Because expression of CD36 within the oral cavity and its effect on digestive secretions are conserved in mice and rats, it is likely that CD36 performs a basic function in the taste bud cells," Philippe Besnard and his fellow authors conclude in the current issue of the Journal of Clinical Investigation. |
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