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| plump up , dietary fat, key, capefeare, atherosclerosis, bbw tgp, distilled water, plump nude , 0385339976, eric himan, product reviews, cheese, anatomy, fat information., restaurants, ahd, dining, | If one takes such a picture of an unswaddled infant hydrogenated oil sleeping at room temperature, "hot spots" can be seen in the skin overlying brown fat deposits in the neck and interscapular area. Brown fat thermogenesis also seems to be of considerable importance to animals coming out of hybernation, allowing them to rewarm. Finally, it seems that hydrogenated oil brown fat plays a non-trivial role in control of body weight, and that mitochondrial uncoupling proteins may be hydrogenated oil one of many factors involved in development of obesity. An interesting demonstration of this is found in a report in which transgenic mice with genetic ablation of brown fat developed obesity in the absense of overeating. References and Reviews Bachman ES, Dhillon H, Zhang C-Y, et al. |
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| In contrast to other cells, including white adipocytes, brown adipocytes express mitochondrial uncoupling dietary fat protein, which gives the cell's mitochondria an dietary fat ability to uncouple oxidative phosphorylation and utilize substrates to generate heat rather than ATP. Exposure to cold leads to sympathetic stimulation of brown adipocyte via norepinephrine binding to beta- adrenergic receptors. As in white fat, sympathetic stimulation promotes hydrolysis of triglyceride, with release of fatty acids and glycerol. However, within brown adipocytes, most fatty acids are immediately oxidized dietary fat in mitochondria and, because of the uncoupling protein, a large amount of heat is produced. This process is part of what is called non-shivering thermogenesis. The heat produced in brown fat can actually be imaged using a thermal (infrared) camera. |
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